The Week 8 NFL schedule features all domestic matchups, including several potential postseason rematches such as Ravens vs. Bills (-3), Vikings vs. Lions (-3.5), Chiefs vs. Broncos (+1.5), and Bears vs. Seahawks (-3). Notable large spreads include Bengals vs. Titans (+13.5), Jaguars vs. Colts (+10.5), and Rams vs. Chargers (+6.5). The Chargers are on a nine-game losing streak and remain the only winless team against the spread this season.
SportsLine's advanced computer model, which simulates every game 10,000 times, has returned more than $5,000 for $100 players on top-rated NFL picks since its inception. Entering Week 8 of the 2026 season, the model is on a 58-51 run on top-rated picks dating back to 2024.
Top Week 8 Predictions
The model's strongest pick has the Steelers (-3.5, 39) covering at home against the Browns. Pittsburgh has won 22 straight home games versus Cleveland dating back to 2004 and is 3-0 against the spread at home this year, while the Browns are 2-2 ATS on the road. Cleveland's 28th-ranked scoring offense is unlikely to keep pace with a Steelers team that has scored 30-plus points in back-to-back home games.
Another highlighted pick: the Rams (-6.5, 45.5) cover versus the Chargers in nearly 60% of simulations. Los Angeles has lost nine straight games, with Justin Herbert throwing twice as many turnovers (12) as touchdowns (6) over that span. The Chargers are also winless against the spread during the streak, while Sean McVay's Rams are 6-2 against the spread in non-conference games since 2025, the second-best mark in the NFL.
Full Week 8 Odds
Key lines include: Panthers at Packers (Thursday) – Packers 27, Panthers 19 final; Cardinals at Cowboys (DAL -7.5, 54.5); Falcons at Buccaneers (TB -1.5, 43.5); Ravens at Bills (BUF -3, 55.5); Browns at Steelers (PIT -3.5, 39); Colts at Jaguars (JAX -10.5, 45.5); Raiders at Jets (NYJ -1.5, 46.5); Vikings at Lions (DET -3, 46); Titans at Bengals (CIN -13.5, 46.5); Chargers at Rams (LAR -6.5, 45.5); Chiefs at Broncos (KC -1.5, 41.5); Patriots at Dolphins (NE -7, 41.5); Eagles at Commanders (WAS -6, 40.5); Bears at Seahawks (Monday, SEA -3, 46.5). The model projects six teams to win by double digits, offering potential value on alternate lines.
