Indianapolis Colts All-Pro guard Quenton Nelson will miss Sunday's game due to a knee injury and has been designated week-to-week, according to a report from ProFootball Talk on NBC Sports. The news was reported by Josh Alper on Friday, November 6, 2026.
Nelson, a multiple-time All-Pro selection and cornerstone of the Colts' offensive line, has been one of the league's premier interior linemen since entering the NFL. His absence represents a significant blow to Indianapolis' offensive front as they navigate the 2026 season.
The week-to-week designation suggests the team will evaluate Nelson's progress on a daily basis, with no definitive timeline established for his return to the lineup.



