Speculation is growing about whether the San Francisco 49ers could pursue Indianapolis Colts running back Jonathan Taylor, according to a report from ProFootball Talk's Mike Florio on November 5, 2026. The 49ers, who have consistently fielded a strong rushing attack, are being mentioned as a potential destination for the All-Pro running back should he become available via trade.
Taylor, 25, has been one of the NFL's most productive running backs since entering the league in 2020, leading the league in rushing yards and touchdowns during the 2021 season. His contract situation with the Colts has been a topic of discussion, fueling trade rumors around the league.
The 49ers' offensive system under head coach Kyle Shanahan has historically maximized running back production, making San Francisco a logical fit for a player of Taylor's caliber. However, any potential acquisition would require significant draft capital and a substantial contract extension.
