Week 10 of the college football season features a slate of tight betting lines and high-profile ranked matchups, particularly within the SEC. The conference showcases Alabama at LSU (-5.5), Georgia at Ole Miss (+3.5), and Texas at Missouri (+2.5). Elsewhere, a top-5 showdown pits No. 1 Miami against No. 4 Notre Dame, with the Fighting Irish favored by 5.5 points. In a historic rivalry, BYU visits Utah with the Utes favored by 5.5 points.
Model Predictions
SportsLine's computer model, which simulates every FBS game 10,000 times and entered the week with an 80-77 record on top-rated picks, has identified several key plays. The model projects Ohio State (-7.5) to cover against Oregon in a 3:30 p.m. ET kickoff, citing the Buckeyes' strong home covering trend and Oregon's struggles against the spread following a win. Another highlighted pick is Oklahoma (+6.5) covering at Florida, with the model noting Florida's quarterback instability and penalty issues. The model also projects the over in that game to hit in 58% of simulations.
Upset Alert
The model forecasts three upsets in ranked matchups according to poll rankings. Full picks for every FBS game are available through SportsLine.
Notable Week 10 Games and Spreads
Wednesday, Nov. 4: Ball State at UMass (-3, 48.5); Toledo at Sacramento State (+25.5, 53.5); Central Michigan at Eastern Michigan (-1.5, 44.5). Thursday, Nov. 5: UTSA at FAU (+7, 73.5); James Madison at Southern Miss (+14.5, 57.5). Friday, Nov. 6: Virginia Tech at SMU (-6, 56.5); South Florida at East Carolina (-2.5, 39.5); Nebraska at Illinois (+4.5, 49.5); New Mexico at Nevada (+9.5, 37.5); TCU at Arizona (-8.5, 43.5). Saturday, Nov. 7: BYU at Utah (-5.5, 48.5); Texas at Missouri (+2.5, 42.5); UCLA at Minnesota (+5.5, 39.5); Alabama at LSU (-5.5, 52.5); Cincinnati at Houston (-10.5, 62.5); Oregon at Ohio State (-7.5, 46.5); Kentucky at Tennessee (-6.5, 50.5); Air Force at Army (-3, 44.5); Miami at Notre Dame (-5.5, 57.5); Michigan State at Michigan (-13.5, 39.5); Georgia at Ole Miss (+3.5, 56.5); Oklahoma at Florida (-6.5, 45.5).
